PrimePCR™ ddPCR™ Expression Probe Assay: STAT2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028748; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5051223
Chromosome Location:   12:56743941-56744915question
Amplicon Length:   119

Gene Information

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN) this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G) in which this protein acts as a transactivator but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Mar 2010]

Gene Symbol:   STAT2
Gene Name:   signal transducer and activator of transcription 2, 113kDa
Aliases:   ISGF-3, MGC59816, P113, STAT113
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000170581
Entrez:   6773
UniGene:   Hs.530595
Chromosome Mapping:   12q13.3

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