PrimePCR™ ddPCR™ Expression Probe Assay: P2RX7, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028622; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5051012
Chromosome Location:   12:121615172-121618224question
Amplicon Length:   116

Gene Information

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq Jul 2010]

Gene Symbol:   P2RX7
Gene Name:   purinergic receptor P2X, ligand-gated ion channel, 7
Aliases:   MGC20089, P2X7
RefSeq:   NC_000012.11 NG_011471.2 NT_009775.17
Ensembl:   ENSG00000089041
Entrez:   5027
UniGene:   Hs.729169
Chromosome Mapping:   12q24

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