PrimePCR™ ddPCR™ Expression Probe Assay: BACE1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028537; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050873
Chromosome Location:   11:117162496-117163838question
Amplicon Length:   73

Gene Information

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases one of which is the protein encoded by this gene. The encoded protein a member of the peptidase A1 protein family is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq May 2011]

Gene Symbol:   BACE1
Gene Name:   beta-site APP-cleaving enzyme 1
Aliases:   ASP2, BACE, FLJ90568, HSPC104, KIAA1149
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000186318
Entrez:   23621
UniGene:   Hs.504003
Chromosome Mapping:   11q23.2-q23.3

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