PrimePCR™ ddPCR™ Expression Probe Assay: RRM2B, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028530; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050859
Chromosome Location:   8:103237133-103238186question
Amplicon Length:   125

Gene Information

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome autosomal dominant progressive external ophthalmoplegia-5 and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq Feb 2010]

Gene Symbol:   RRM2B
Gene Name:   ribonucleotide reductase M2 B (TP53 inducible)
Aliases:   DKFZp686M05248, MGC102856, MGC42116, MTDPS8A, MTDPS8B, P53R2
RefSeq:   NC_000008.10 NT_008046.16 NG_016617.1
Ensembl:   ENSG00000048392
Entrez:   50484
UniGene:   Hs.512592
Chromosome Mapping:   8q23.1

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