PrimePCR™ ddPCR™ Expression Probe Assay: CKAP5, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028491; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050791
Chromosome Location:   11:46774216-46774993question
Amplicon Length:   149

Gene Information

This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2 which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2011]

Gene Symbol:   CKAP5
Gene Name:   cytoskeleton associated protein 5
Aliases:   CHTOG, FLJ35359, KIAA0097, MSPS, TOG, TOGp, ch-TOG
RefSeq:   NC_000011.9 NT_009237.18
Ensembl:   ENSG00000175216
Entrez:   9793
UniGene:   Hs.201253
Chromosome Mapping:   11p11.2

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