PrimePCR™ ddPCR™ Expression Probe Assay: APEX1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028481; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050773
Chromosome Location:   14:20924202-20924895question
Amplicon Length:   98

Gene Information

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq Jul 2008]

Gene Symbol:   APEX1
Gene Name:   APEX nuclease (multifunctional DNA repair enzyme) 1
Aliases:   APE, APE1, APEN, APEX, APX, HAP1, REF1
RefSeq:   NC_000014.8 NG_008718.1 NT_026437.12
Ensembl:   ENSG00000100823
Entrez:   328
UniGene:   Hs.73722
Chromosome Mapping:   14q11.2

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