PrimePCR™ ddPCR™ Expression Probe Assay: MAPKAPK3, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028455; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050724
Chromosome Location:   3:50677850-50679174question
Amplicon Length:   94

Gene Information

This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs) act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with phosphorylate and repress the activity of E47 which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq Sep 2011]

Gene Symbol:   MAPKAPK3
Gene Name:   mitogen-activated protein kinase-activated protein kinase 3
Aliases:   3PK, MAPKAP3
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000114738
Entrez:   7867
UniGene:   Hs.234521
Chromosome Mapping:   3p21.3

Number Description Download