PrimePCR™ ddPCR™ Expression Probe Assay: SHMT1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028410; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050652
Chromosome Location:   17:18257079-18259308question
Amplicon Length:   132

Gene Information

This gene encodes the cellular form of serine hydroxymethyltransferase a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 510-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine thymidylate and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described but their biological validity has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   SHMT1
Gene Name:   serine hydroxymethyltransferase 1 (soluble)
Aliases:   CSHMT, MGC15229, MGC24556, SHMT
RefSeq:   NC_000017.10 NG_017111.1 NT_010718.16
Ensembl:   ENSG00000176974
Entrez:   6470
UniGene:   Hs.513987
Chromosome Mapping:   17p11.2

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