PrimePCR™ ddPCR™ Expression Probe Assay: TAB2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027485; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049036
Chromosome Location:   6:149691193-149699264question
Amplicon Length:   124

Gene Information

The protein encoded by this gene is an activator of MAP3K7/TAK1 which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6 MAP3K7 and TAB1 thus serves as an adaptor linking MAP3K7 and TRAF6. This protein TAB1 and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK) which may regulate the development and function of osteoclasts. [provided by RefSeq Jul 2008]

Gene Symbol:   TAB2
Gene Name:   TGF-beta activated kinase 1/MAP3K7 binding protein 2
Aliases:   CHTD2, FLJ21885, KIAA0733, MAP3K7IP2
RefSeq:   NC_000006.11 NG_012301.1 NG_021386.1 NT_025741.15
Ensembl:   ENSG00000055208
Entrez:   23118
UniGene:   Hs.269775
Chromosome Mapping:   6q25.1

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