PrimePCR™ ddPCR™ Expression Probe Assay: COX4I2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027261; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048687
Chromosome Location:   20:30231293-30232676question
Amplicon Length:   122

Gene Information

Cytochrome c oxidase (COX) the terminal enzyme of the mitochondrial respiratory chain catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene however the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq Jul 2008]

Gene Symbol:   COX4I2
Gene Name:   cytochrome c oxidase subunit IV isoform 2 (lung)
Aliases:   COX4, COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2
RefSeq:   NC_000020.10 NG_012180.1 NT_011362.10
Ensembl:   ENSG00000131055
Entrez:   84701
UniGene:   Hs.277101
Chromosome Mapping:   20q11.21

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