PrimePCR™ ddPCR™ Expression Probe Assay: BPNT1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027146; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048501
Chromosome Location:   1:220247340-220253121question
Amplicon Length:   97

Gene Information

BPNT1 also called bisphosphate 3-prime-nucleotidase or BPntase is a member of a magnesium-dependent phosphomonoesterase family. Lithium a major drug used to treat manic depression acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq Jul 2008]

Gene Symbol:   BPNT1
Gene Name:   3'(2'), 5'-bisphosphate nucleotidase 1
Aliases:   PIP
RefSeq:   NC_000001.10 NT_167186.1
Ensembl:   ENSG00000162813
Entrez:   10380
UniGene:   Hs.406134
Chromosome Mapping:   1q41

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