PrimePCR™ ddPCR™ Expression Probe Assay: FGR, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027130; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048470
Chromosome Location:   1:27943801-27949599question
Amplicon Length:   123

Gene Information

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation a PTK domain and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs respectively. The protein localizes to plasma membrane ruffles and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants encoding the same protein have been identified. [provided by RefSeq Jul 2008]

Gene Symbol:   FGR
Gene Name:   Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
Aliases:   FLJ43153, MGC75096, SRC2, c-fgr, c-src2, p55-Fgr, p55c-fgr, p58c-fgr
RefSeq:   NC_000001.10 NT_004610.19
Ensembl:   ENSG00000000938
Entrez:   2268
UniGene:   Hs.1422
Chromosome Mapping:   1p36.2-p36.1

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