PrimePCR™ ddPCR™ Expression Probe Assay: DPYD, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026939; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048141
Chromosome Location:   1:98187143-98206029question
Amplicon Length:   137

Gene Information

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq May 2009]

Gene Symbol:   DPYD
Gene Name:   dihydropyrimidine dehydrogenase
Aliases:   DHP, DHPDHASE, DPD, MGC132008, MGC70799
RefSeq:   NC_000001.10 NG_008807.1 NT_032977.9
Ensembl:   ENSG00000188641
Entrez:   1806
UniGene:   Hs.335034
Chromosome Mapping:   1p22

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