PrimePCR™ ddPCR™ Expression Probe Assay: ATP6V1B2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026916; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048101
Chromosome Location:   8:20061995-20067872question
Amplicon Length:   140

Gene Information

This gene encodes a component of vacuolar ATPase (V-ATPase) a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting zymogen activation receptor-mediated endocytosis and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A three B and two G subunits as well as a C D E F and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq Jul 2008]

Gene Symbol:   ATP6V1B2
Gene Name:   ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
Aliases:   ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2
RefSeq:   NC_000008.10 NT_167187.1
Ensembl:   ENSG00000147416
Entrez:   526
UniGene:   Hs.295917
Chromosome Mapping:   8p21.3

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