PrimePCR™ ddPCR™ Expression Probe Assay: ABCG8, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026840; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5047967
Chromosome Location:   2:44079927-44099208question
Amplicon Length:   145

Gene Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level promote excretion of cholesterol and sterols into bile and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver intestine and gallbladder. This gene is tandemly arrayed on chromosome 2 in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis and have been observed in patients with sitosterolemia. [provided by RefSeq Jul 2008]

Gene Symbol:   ABCG8
Gene Name:   ATP-binding cassette, sub-family G (WHITE), member 8
Aliases:   GBD4, MGC142217, STSL
RefSeq:   NC_000002.11 NG_008883.1 NG_008884.1 NT_022184.15
Ensembl:   ENSG00000143921
Entrez:   64241
UniGene:   Hs.413931
Chromosome Mapping:   2p21

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