PrimePCR™ ddPCR™ Expression Probe Assay: MMP13, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026824; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5047936
Chromosome Location:   11:102820839-102822790question
Amplicon Length:   138

Gene Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq Jul 2008]

Gene Symbol:   MMP13
Gene Name:   matrix metallopeptidase 13 (collagenase 3)
Aliases:   CLG3, MANDP1
RefSeq:   NC_000011.9 NG_021404.1 NT_033899.8
Ensembl:   ENSG00000137745
Entrez:   4322
UniGene:   Hs.2936
Chromosome Mapping:   11q22.3

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