PrimePCR™ ddPCR™ Expression Probe Assay: MBTPS1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026724; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5047760
Chromosome Location:   16:84092992-84094377question
Amplicon Length:   103

Gene Information

The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs) a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq Jul 2008]

Gene Symbol:   MBTPS1
Gene Name:   membrane-bound transcription factor peptidase, site 1
Aliases:   KIAA0091, MGC138711, MGC138712, PCSK8, S1P, SKI-1
RefSeq:   NC_000016.9 NT_010498.15
Ensembl:   ENSG00000140943
Entrez:   8720
UniGene:   Hs.75890
Chromosome Mapping:   16,16q24

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