PrimePCR™ ddPCR™ Expression Probe Assay: CELSR1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026524; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5047408
Chromosome Location:   22:46768900-46773032question
Amplicon Length:   100

Gene Information

The protein encoded by this gene is a member of the flamingo subfamily part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq Jul 2008]

Gene Symbol:   CELSR1
Gene Name:   cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
Aliases:   CDHF9, DKFZp434P0729, FMI2, HFMI2, ME2
RefSeq:   NC_000022.10 NT_011520.12
Ensembl:   ENSG00000075275
Entrez:   9620
UniGene:   Hs.252387
Chromosome Mapping:   22q13.3

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