PrimePCR™ ddPCR™ Expression Probe Assay: POT1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026505; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5047371
Chromosome Location:   7:124499088-124503454question
Amplicon Length:   100

Gene Information

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres regulating telomere length and protecting chromosome ends from illegitimate recombination catastrophic chromosome instability and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   POT1
Gene Name:   protection of telomeres 1 homolog (S. pombe)
Aliases:   DKFZp586D211, HPOT1
RefSeq:   NC_000007.13 NT_007933.15
Ensembl:   ENSG00000128513
Entrez:   25913
UniGene:   Hs.31968
Chromosome Mapping:   7q31.33

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