PrimePCR™ ddPCR™ Expression Probe Assay: CYP19A1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026454; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5047275
Chromosome Location:   15:51520064-51529115question
Amplicon Length:   97

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq Jul 2008]

Gene Symbol:   CYP19A1
Gene Name:   cytochrome P450, family 19, subfamily A, polypeptide 1
Aliases:   ARO, ARO1, CPV1, CYAR, CYP19, MGC104309, P-450AROM
RefSeq:   NC_000015.9 NT_010194.17 NG_007982.1
Ensembl:   ENSG00000137869
Entrez:   1588
UniGene:   Hs.260074
Chromosome Mapping:   15q21.1

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