This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026442; Intron-spanning
This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase Rab-like GTPase activator and myotubularins domain the Rac-induced recruitment domain the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9 enhancer-of-zeste and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 13-bisphosphate. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq Mar 2009]