PrimePCR™ ddPCR™ Expression Probe Assay: RRM1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0058446; exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5046087
Chromosome Location:   11:4139602-4141080question
Amplicon Length:   66

Gene Information

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5 an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome Wilms tumor rhabdomyosarcoma adrenocrotical carcinoma and lung ovarian and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq Jul 2008]

Gene Symbol:   RRM1
Gene Name:   ribonucleotide reductase M1
Aliases:   R1, RIR1, RR1
RefSeq:   NC_000011.9 NG_016277.1 NG_027992.1 NT_009237.18
Ensembl:   ENSG00000167325
Entrez:   6240
UniGene:   Hs.445705
Chromosome Mapping:   11p15.5

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