PrimePCR™ ddPCR™ Expression Probe Assay: KCNAB2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0057740; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044938
Chromosome Location:   1:6158729-6158839question
Amplicon Length:   81

Gene Information

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release heart rate insulin secretion neuronal excitability epithelial electrolyte transport smooth muscle contraction and cell volume. Four sequence-related potassium channel genes - shaker shaw shab and shal - have been identified in Drosophila and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel voltage-gated shaker-related subfamily. This member is one of the beta subunits which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq Dec 2010]

Gene Symbol:   KCNAB2
Gene Name:   potassium voltage-gated channel, shaker-related subfamily, beta member 2
Aliases:   AKR6A5, HKvbeta2, HKvbeta2.1, HKvbeta2.2, KCNA2B, KV-BETA-2, MGC117289
RefSeq:   NC_000001.10 NT_021937.19
Ensembl:   ENSG00000069424
Entrez:   8514
UniGene:   Hs.440497
Chromosome Mapping:   1p36.3

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