PrimePCR™ ddPCR™ Expression Probe Assay: MRPL48, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054379; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5041276
Chromosome Location:   11:73536820-73555970question
Amplicon Length:   111

Gene Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species the proteins comprising the mitoribosome differ greatly in sequence and sometimes in biochemical properties which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. [provided by RefSeq Jul 2008]

Gene Symbol:   MRPL48
Gene Name:   mitochondrial ribosomal protein L48
Aliases:   FLJ17047, FLJ99260, HSPC290, L48MT, MGC13323, MRP-L48
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000175581
Entrez:   51642
UniGene:   Hs.503239
Chromosome Mapping:   11q13.4

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