PrimePCR™ ddPCR™ Expression Probe Assay: TNK1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0054298; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5041133
Chromosome Location:   17:7291941-7292123question
Amplicon Length:   70

Gene Information

The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways mediating cellular proliferation survival and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues thus may function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway and knockout mice have been shown to develop spontaneous tumors suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2011]

Gene Symbol:   TNK1
Gene Name:   tyrosine kinase, non-receptor, 1
Aliases:   MGC46193
RefSeq:   NC_000017.10 NT_010718.16
Ensembl:   ENSG00000174292
Entrez:   8711
UniGene:   Hs.203420
Chromosome Mapping:   17p13.1

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