PrimePCR™ ddPCR™ Expression Probe Assay: CA5B, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053879; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040399
Chromosome Location:   X:15768125-15768261question
Amplicon Length:   107

Gene Information

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes including respiration calcification acid-base balance bone resorption and the formation of aqueous humor cerebrospinal fluid saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA CA VA. It has a wider tissue distribution than CA VA which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq Jul 2008]

Gene Symbol:   CA5B
Gene Name:   carbonic anhydrase VB, mitochondrial
Aliases:   CA-VB, MGC39962
RefSeq:   NC_000023.10 NG_012746.1 NG_012766.1 NT_167197.1
Ensembl:   ENSG00000169239
Entrez:   11238
UniGene:   Hs.728980
Chromosome Mapping:   Xp21.1

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