PrimePCR™ ddPCR™ Expression Probe Assay: RGS14, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053876; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040397
Chromosome Location:   5:176798985-176799099question
Amplicon Length:   85

Gene Information

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain two Raf-like Ras-binding domains (RBDs) and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding through its GoLoco domain to specific types of activated GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP) the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers forming inactive G-protein heterotrimers thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   RGS14
Gene Name:   regulator of G-protein signaling 14
Aliases:   Not Available
RefSeq:   NC_000005.9 NT_023133.13
Ensembl:   ENSG00000169220
Entrez:   10636
UniGene:   Hs.9347
Chromosome Mapping:   5q35.3

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