PrimePCR™ ddPCR™ Expression Probe Assay: INHBB, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053297; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039330
Chromosome Location:   2:121107516-121107630question
Amplicon Length:   85

Gene Information

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore the beta B subunit forms a homodimer activin B and also joins with the beta A subunit to form a heterodimer activin AB both of which stimulate FSH secretion. [provided by RefSeq Jul 2008]

Gene Symbol:   INHBB
Gene Name:   inhibin, beta B
Aliases:   MGC157939
RefSeq:   NC_000002.11 NT_022135.16
Ensembl:   ENSG00000163083
Entrez:   3625
UniGene:   Hs.1735
Chromosome Mapping:   2cen-q13

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