PrimePCR™ ddPCR™ Expression Probe Assay: CRH, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052638; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038161
Chromosome Location:   8:67088779-67088925question
Amplicon Length:   117

Gene Information

Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus this protein is also synthesized in peripheral tissues such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition suggesting that in addition to its metabolic functions this protein may act as a trigger for parturition. [provided by RefSeq Apr 2010]

Gene Symbol:   CRH
Gene Name:   corticotropin releasing hormone
Aliases:   CRF
RefSeq:   NC_000008.10 NG_016127.1 NT_008183.19
Ensembl:   ENSG00000147571
Entrez:   1392
UniGene:   Hs.75294
Chromosome Mapping:   8q13

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