PrimePCR™ ddPCR™ Expression Probe Assay: CYP2E1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051588; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5036296
Chromosome Location:   10:135350644-135350745question
Amplicon Length:   72

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol the diabetic state and starvation. The enzyme metabolizes both endogenous substrates such as ethanol acetone and acetal as well as exogenous substrates including benzene carbon tetrachloride ethylene glycol and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates this enzyme may be involved in such varied processes as gluconeogenesis hepatic cirrhosis diabetes and cancer. [provided by RefSeq Jul 2008]

Gene Symbol:   CYP2E1
Gene Name:   cytochrome P450, family 2, subfamily E, polypeptide 1
Aliases:   CPE1, CYP2E, P450-J, P450C2E
RefSeq:   NC_000010.10 NG_008383.1 NT_008818.16
Ensembl:   ENSG00000130649
Entrez:   1571
UniGene:   Hs.12907
Chromosome Mapping:   10q24.3-qter

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