PrimePCR™ ddPCR™ Expression Probe Assay: RUNX2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051329; exonic

Fluorophore:   FAM
List Price:    $213.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035834
Chromosome Location:   6:45459747-45479990question
Amplicon Length:   83

Gene Information

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or with more affinity as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq Jul 2008]

Gene Symbol:   RUNX2
Gene Name:   runt-related transcription factor 2
Aliases:   AML3, CBFA1, CCD, CCD1, MGC120022, MGC120023, OSF-2, OSF2, PEA2aA, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1
RefSeq:   NC_000006.11 NT_007592.15 NG_008020.1
Ensembl:   ENSG00000124813
Entrez:   860
UniGene:   Hs.535845
Chromosome Mapping:   6p21

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