PrimePCR™ ddPCR™ Expression Probe Assay: CBX3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051212; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035622
Chromosome Location:   7:26252664-26252810question
Amplicon Length:   117

Gene Information

At the nuclear envelope the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR have been found for this gene.[provided by RefSeq Mar 2011]

Gene Symbol:   CBX3
Gene Name:   chromobox homolog 3
Aliases:   HECH, HP1-GAMMA, HP1Hs-gamma
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000122565
Entrez:   11335
UniGene:   Hs.381189
Chromosome Mapping:   7p15.2

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