PrimePCR™ ddPCR™ Expression Probe Assay: CAT, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051176; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035557
Chromosome Location:   11:34472543-34473624question
Amplicon Length:   74

Gene Information

This gene encodes catalase a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes asthma Alzheimer's disease systemic lupus erythematosus rheumatoid arthritis and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but to date acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq Oct 2009]

Gene Symbol:   CAT
Gene Name:   catalase
Aliases:   MGC138422, MGC138424
RefSeq:   NC_000011.9 NG_013339.1 NT_009237.18
Ensembl:   ENSG00000121691
Entrez:   847
UniGene:   Hs.502302
Chromosome Mapping:   11p13

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