PrimePCR™ ddPCR™ Expression Probe Assay: IAPP, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051161; exonic

Fluorophore:   HEX
List Price:    $213.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035529
Chromosome Location:   12:21531174-21531325question
Amplicon Length:   122

Gene Information

Islet or insulinoma amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time a direct causative role for amylin has been harder to establish. Studies suggest that amylin like the related beta-amyloid (Abeta) associated with Alzheimer's disease can induce apoptotic cell-death in particular cultured cells an effect that may be relevant to the development of type II diabetes. [provided by RefSeq Apr 2011]

Gene Symbol:   IAPP
Gene Name:   islet amyloid polypeptide
Aliases:   DAP, IAP
RefSeq:   NC_000012.11 NT_009714.17
Ensembl:   ENSG00000121351
Entrez:   3375
UniGene:   Hs.46835
Chromosome Mapping:   12p12.1

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