PrimePCR™ ddPCR™ Expression Probe Assay: SDHB, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050983; exonic

Fluorophore:   HEX
List Price:    $213.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5035263
Chromosome Location:   1:17345335-17349109question
Amplicon Length:   96

Gene Information

Complex II of the respiratory chain which is specifically involved in the oxidation of succinate carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq Jul 2008]

Gene Symbol:   SDHB
Gene Name:   succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Aliases:   FLJ92337, IP, PGL4, SDH, SDH1, SDH2, SDHIP
RefSeq:   NC_000001.10 NG_012340.1 NT_004610.19
Ensembl:   ENSG00000117118
Entrez:   6390
UniGene:   Hs.465924
Chromosome Mapping:   1p36.1-p35

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