PrimePCR™ ddPCR™ Expression Probe Assay: USP5, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050651; exonic

 
Fluorophore:   HEX
List Price:    $213.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034639
Chromosome Location:   12:6961366-6964585question
Amplicon Length:   80

Gene Information

Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure receptor function and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism starting at the proximal end of the chain (Wilkinson et al. 1995 [PubMed 7578059]).[supplied by OMIM Mar 2010]

Gene Symbol:   USP5
Gene Name:   ubiquitin specific peptidase 5 (isopeptidase T)
Aliases:   ISOT
RefSeq:   NC_000012.11 NG_011948.1 NT_009759.16
Ensembl:   ENSG00000111667
Entrez:   8078
UniGene:   Hs.631661
Chromosome Mapping:   12p13

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