PrimePCR™ ddPCR™ Expression Probe Assay: PLOD3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050408; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034218
Chromosome Location:   7:100859815-100860455question
Amplicon Length:   84

Gene Information

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq Jul 2008]

Gene Symbol:   PLOD3
Gene Name:   procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
Aliases:   LH3
RefSeq:   NC_000007.13 NG_012148.1 NT_007933.15
Ensembl:   ENSG00000106397
Entrez:   8985
UniGene:   Hs.153357
Chromosome Mapping:   7q22

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