PrimePCR™ ddPCR™ Expression Probe Assay: SERPINE1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050406; exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034215
Chromosome Location:   7:100781499-100781640question
Amplicon Length:   112

Gene Information

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA) and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Sep 2009]

Gene Symbol:   SERPINE1
Gene Name:   serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Aliases:   PAI, PAI-1, PAI1, PLANH1
RefSeq:   NC_000007.13 NG_013213.1 NT_007933.15
Ensembl:   ENSG00000106366
Entrez:   5054
UniGene:   Hs.414795
Chromosome Mapping:   7q21.3-q22

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