PrimePCR™ ddPCR™ Expression Probe Assay: CASP2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050394; exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034195
Chromosome Location:   7:142985599-142988733question
Amplicon Length:   95

Gene Information

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways cell cycle maintenance and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Jan 2011]

Gene Symbol:   CASP2
Gene Name:   caspase 2, apoptosis-related cysteine peptidase
Aliases:   CASP-2, ICH1, NEDD-2, NEDD2
RefSeq:   NC_000007.13 NT_007914.15
Ensembl:   ENSG00000106144
Entrez:   835
UniGene:   Hs.368982
Chromosome Mapping:   7q34-q35

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