PrimePCR™ ddPCR™ Expression Probe Assay: CHN2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050389; exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034189
Chromosome Location:   7:29548924-29549013question
Amplicon Length:   60

Gene Information

This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   CHN2
Gene Name:   chimerin (chimaerin) 2
Aliases:   ARHGAP3, BCH, MGC138360, RHOGAP3
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000106069
Entrez:   1124
UniGene:   Hs.654611
Chromosome Mapping:   7p15.3

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