PrimePCR™ ddPCR™ Expression Probe Assay: BRAT1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050386; exonic

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034182
Chromosome Location:   7:2578886-2579196question
Amplicon Length:   89

Gene Information

The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq Mar 2012]

Gene Symbol:   BRAT1
Gene Name:   BRCA1-associated ATM activator 1
Aliases:   BAAT1, C7orf27, MGC22916
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000106009
Entrez:   221927
UniGene:   Hs.520623
Chromosome Mapping:   7p22.3

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