PrimePCR™ ddPCR™ Expression Probe Assay: ATP6V0A4, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050374; exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034165
Chromosome Location:   7:138432189-138433914question
Amplicon Length:   94

Gene Information

This gene encodes a component of vacuolar ATPase (V-ATPase) a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting zymogen activation receptor-mediated endocytosis and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits two G subunits plus the C D E F and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a c c' c'' and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing. [provided by RefSeq Jul 2008]

Gene Symbol:   ATP6V0A4
Gene Name:   ATPase, H+ transporting, lysosomal V0 subunit a4
Aliases:   A4, ATP6N1B, ATP6N2, MGC130016, MGC130017, RDRTA2, RTA1C, RTADR, STV1, VPH1, VPP2
RefSeq:   NC_000007.13 NG_008145.1 NT_007933.15
Ensembl:   ENSG00000105929
Entrez:   50617
UniGene:   Hs.98967
Chromosome Mapping:   7q34

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