PrimePCR™ ddPCR™ Expression Probe Assay: PON2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050367; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034152
Chromosome Location:   7:95034690-95034786question
Amplicon Length:   67

Gene Information

This gene encodes a member of the paraoxonase gene family which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues membrane-bound and may act as a cellular antioxidant protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones important bacterial quorum-sensing mediators suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   PON2
Gene Name:   paraoxonase 2
Aliases:   Not Available
RefSeq:   NC_000007.13 NG_008725.1 NT_007933.15
Ensembl:   ENSG00000105854
Entrez:   5445
UniGene:   Hs.731646
Chromosome Mapping:   7q21.3

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