This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050342; exonic
This gene encodes a member of the DNase family. The protein located in the lysosome hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized DNASE2*L (low activity) and DNASE2*H (high activity) that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq Jul 2008]