PrimePCR™ ddPCR™ Expression Probe Assay: CYTH2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050333; exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034093
Chromosome Location:   19:48976608-48977249question
Amplicon Length:   86

Gene Information

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif a central Sec7 domain and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1 ARF3 and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Aug 2008]

Gene Symbol:   CYTH2
Gene Name:   cytohesin 2
Aliases:   ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000105443
Entrez:   9266
UniGene:   Hs.144011
Chromosome Mapping:   19q13.33

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