PrimePCR™ ddPCR™ Expression Probe Assay: MRPL4, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050321; exonic

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034073
Chromosome Location:   19:10368906-10368997question
Amplicon Length:   62

Gene Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species the proteins comprising the mitoribosome differ greatly in sequence and sometimes in biochemical properties which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified alternatively spliced variants that encode different protein isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   MRPL4
Gene Name:   mitochondrial ribosomal protein L4
Aliases:   CGI-28, L4mt, MGC16367, MGC2681
RefSeq:   NC_000019.9 NT_011295.11
Ensembl:   ENSG00000105364
Entrez:   51073
UniGene:   Hs.279652
Chromosome Mapping:   19p13.2

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