PrimePCR™ ddPCR™ Expression Probe Assay: BBC3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050318; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5034069
Chromosome Location:   19:47724936-47725131question
Amplicon Length:   166

Gene Information

This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq Dec 2011]

Gene Symbol:   BBC3
Gene Name:   BCL2 binding component 3
Aliases:   FLJ42994, JFY1, PUMA
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000105327
Entrez:   27113
UniGene:   Hs.467020
Chromosome Mapping:   19q13.3-q13.4

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