PrimePCR™ ddPCR™ Expression Probe Assay: STK24, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050193; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033845
Chromosome Location:   13:99114028-99114140question
Amplicon Length:   83

Gene Information

The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast members of the GCK subfamily (see MAP4K2; MIM 603166) also called the Sps1 subfamily have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al. 2000 [PubMed 10644707]).[supplied by OMIM Mar 2008]

Gene Symbol:   STK24
Gene Name:   serine/threonine kinase 24
Aliases:   MST3, MST3B, STE20, STK3
RefSeq:   NC_000013.10 NT_009952.14
Ensembl:   ENSG00000102572
Entrez:   8428
UniGene:   Hs.508514
Chromosome Mapping:   13q31.2-q32.3

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