PrimePCR™ ddPCR™ Expression Probe Assay: F9, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050157; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033782
Chromosome Location:   X:138643758-138643856question
Amplicon Length:   69

Gene Information

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions membrane phospholipids and factor VIII. Alterations of this gene including point mutations insertions and deletions cause factor IX deficiency which is a recessive X-linked disorder also called hemophilia B or Christmas disease. [provided by RefSeq Jul 2008]

Gene Symbol:   F9
Gene Name:   coagulation factor IX
Aliases:   FIX, HEMB, MGC129641, MGC129642, P19, PTC
RefSeq:   NC_000023.10 NG_007994.1 NT_011786.16
Ensembl:   ENSG00000101981
Entrez:   2158
UniGene:   Hs.522798
Chromosome Mapping:   Xq27.1-q27.2

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