PrimePCR™ ddPCR™ Expression Probe Assay: RBBP8, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050144; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5033757
Chromosome Location:   18:20516729-20516864question
Amplicon Length:   106

Gene Information

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation DNA repair and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist but their full-length natures have not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   RBBP8
Gene Name:   retinoblastoma binding protein 8
Aliases:   CTIP, RIM, SAE2
RefSeq:   NC_000018.9 NG_012121.1 NT_010966.14
Ensembl:   ENSG00000101773
Entrez:   5932
UniGene:   Hs.546282
Chromosome Mapping:   18q11.2

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